Viagra, or sildenafil, works by inhibiting an enzyme called phosphodiesterase-5 (PDE5). PDE5 breaks down cyclic guanosine monophosphate (cGMP), a molecule crucial for blood vessel relaxation. By blocking PDE5, Viagra increases cGMP levels.
Increased cGMP and Blood Flow
Higher cGMP levels cause the smooth muscles in the blood vessels of the penis to relax. This relaxation leads to increased blood flow into the penis, facilitating an erection. This process is triggered by sexual stimulation; Viagra doesn’t cause erections independently.
Specific Effects and Considerations
Viagra’s effects are localized primarily to the penis’s blood vessels. The duration of its action is typically four to five hours, although individual responses vary. It’s vital to consult a doctor before using Viagra, especially if you have pre-existing heart conditions or take other medications. Potential side effects include headaches, flushing, and nasal congestion. Proper dosage is paramount for safe and effective use.
