Orlistat works by preventing the absorption of dietary fats. Specifically, it inhibits pancreatic lipases, enzymes your body uses to break down fats in your food. This means a portion of the fat you consume passes through your digestive system undigested and is eliminated in your stool.
How much fat does Orlistat block?
Studies show Orlistat can block the absorption of roughly 25-30% of dietary fat. This isn’t a complete blockage; some fat absorption still occurs.
What are the implications?
This reduction in fat absorption contributes to weight loss. Fewer calories from fat are absorbed, creating a calorie deficit. Remember, Orlistat is most effective when combined with a reduced-calorie diet and regular exercise.
Important Considerations:
Because Orlistat prevents fat absorption, you may experience some gastrointestinal side effects like oily stools, gas, and urgent bowel movements. These are usually mild and temporary. Also, Orlistat can interfere with the absorption of fat-soluble vitamins; discuss supplementation with your doctor.
