Understanding Orlistat 120mg and its Mechanism

Orlistat 120mg works by inhibiting pancreatic lipases, enzymes your body uses to break down dietary fats. This prevents the absorption of approximately 30% of ingested fat.

Specifically, Orlistat binds to the active site of these lipases, rendering them inactive. Undigested fats then pass through your digestive system and are eliminated in your stool.

This mechanism leads to reduced calorie intake from fat, contributing to weight loss. However, remember that Orlistat is most effective when combined with a reduced-calorie diet and increased physical activity.

Mechanism Stage Description
Lipase Inhibition Orlistat blocks pancreatic lipases.
Fat Digestion Reduction Less fat is broken down and absorbed.
Fecal Fat Excretion Undigested fat is eliminated through stool.
Calorie Reduction Reduced fat absorption leads to fewer calories absorbed.

Potential side effects include oily stools, loose stools, and frequent bowel movements. These usually lessen as your body adjusts. Consult your doctor before starting Orlistat, especially if you have pre-existing health conditions.