Levitra, or vardenafil, works by increasing blood flow to the penis. This happens because it inhibits a specific enzyme called phosphodiesterase-5 (PDE5). PDE5 normally breaks down cyclic guanosine monophosphate (cGMP), a molecule crucial for penile erection. By blocking PDE5, Levitra allows cGMP levels to rise, leading to relaxation of smooth muscles in the penis and increased blood flow. This enhanced blood flow facilitates an erection in response to sexual stimulation.
Specifics on PDE5 Inhibition
The selective inhibition of PDE5 is key. Levitra’s impact on other PDE isoforms is minimal, reducing potential side effects. This selectivity ensures its primary action focuses on improving erectile function without significantly affecting other bodily systems. The higher the concentration of cGMP, the stronger the vasodilation and the easier erection becomes.
Considerations for Optimal Function
Remember, Levitra requires sexual stimulation to work. It doesn’t spontaneously cause erections. Optimal results often depend on factors like dosage, individual health conditions, and the presence of other medications. Always consult a healthcare professional before taking Levitra or any other medication for erectile dysfunction.
