Cialis, containing tadalafil, works by inhibiting a specific enzyme, phosphodiesterase-5 (PDE5). This enzyme usually breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for penile erection.
By blocking PDE5, tadalafil increases cGMP levels. Higher cGMP levels relax the smooth muscles in the blood vessels of the penis, allowing increased blood flow. This increased blood flow facilitates and sustains an erection in response to sexual stimulation.
The effect is selective. Tadalafil primarily affects the penis, minimizing systemic effects. Its longer half-life, around 17.5 hours, allows for a more extended period of potential effectiveness compared to some other erectile dysfunction medications.
Remember: Tadalafil’s action requires sexual stimulation. It doesn’t automatically cause an erection. It enhances the body’s natural response to sexual stimulation.
Note: This information is for educational purposes only and does not constitute medical advice. Always consult a healthcare professional before starting any new medication.
