Avanafil works by selectively inhibiting phosphodiesterase type 5 (PDE5) enzymes. This inhibition increases the concentration of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum.
Elevated cGMP levels relax these smooth muscles, allowing increased blood flow into the penis. This leads to penile erection.
Avanafil’s specific PDE5 selectivity contributes to its relatively short half-life, resulting in quicker onset and shorter duration of action compared to other PDE5 inhibitors.
The speed of action depends on several factors including individual metabolism and dosage. For optimal results, follow your doctor’s prescribed dosage and timing instructions carefully.
Remember, always consult your physician before starting any new medication, including Avanafil, to ensure its suitability and to discuss potential side effects.
