Always inform your doctor about all medications you take, including over-the-counter drugs, supplements, and herbal remedies, before starting Tadalafil 5mg. This includes nitrates, commonly used to treat chest pain (angina). Combining Tadalafil with nitrates can cause a dangerous drop in blood pressure.
Medication Interactions to Note
Certain medications can significantly affect Tadalafil’s efficacy or increase the risk of side effects. Alpha-blockers, often prescribed for high blood pressure or enlarged prostate, can interact, potentially causing dizziness or fainting. Similarly, medications used to treat HIV/AIDS, such as ritonavir or saquinavir, can raise Tadalafil levels in your blood, potentially increasing the likelihood of side effects. Always consult your doctor or pharmacist about potential interactions.
Specific Interactions Table
| Nitrates (e. g., nitroglycerin) | Significant | Dangerous drop in blood pressure |
| Alpha-blockers (e. g., tamsulosin) | Moderate | Dizziness, fainting |
| HIV protease inhibitors (e. g., ritonavir) | Significant | Increased Tadalafil blood levels, higher risk of side effects |
| Azole antifungals (e. g., ketoconazole) | Moderate | Increased Tadalafil blood levels |
Grapefruit Juice Interaction
Avoid grapefruit juice while taking Tadalafil 5mg. Grapefruit can increase the amount of Tadalafil in your bloodstream, potentially leading to more intense side effects.
