Prednisone, a corticosteroid, reduces inflammation by binding to intracellular receptors, influencing gene expression and decreasing the production of inflammatory mediators like cytokines. This mechanism provides its therapeutic value.
Prednisone treats various conditions. Autoimmune diseases like rheumatoid arthritis and lupus benefit significantly. It also manages allergic reactions, inflammatory bowel disease, and certain cancers. Doctors also prescribe it for severe asthma attacks and some skin conditions.
However, prednisone’s potent effects come with potential side effects. Long-term use can cause weight gain, increased blood sugar, and weakened bones (osteoporosis). Other possible effects include high blood pressure, mood changes, and increased risk of infection. Short-term use usually presents fewer issues.
| Metabolic | Increased appetite, weight gain, high blood sugar, high cholesterol |
| Musculoskeletal | Muscle weakness, bone thinning, easy bruising |
| Cardiovascular | High blood pressure, fluid retention |
| Gastrointestinal | Heartburn, ulcers |
| Psychiatric | Mood swings, insomnia, anxiety |
| Infections | Increased susceptibility to infections |
Always consult your doctor before starting or stopping prednisone. They will assess your condition and determine the optimal dosage and duration of treatment, minimizing potential risks.
