Always inform your doctor about all medications you take, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil. This is crucial for safe use.
Heart Conditions
Sildenafil can lower blood pressure. If you have heart problems, including angina, heart failure, or irregular heartbeat, discuss Sildenafil with your doctor. They will assess your suitability for this medication. Avoid strenuous activity after taking Sildenafil, especially if you experience chest pain or discomfort.
Drug Interactions
Certain medications interact negatively with Sildenafil. These include nitrates (used to treat angina), alpha-blockers (used to treat high blood pressure and prostate problems), and some antifungals. Combining these can cause a dangerous drop in blood pressure. Always check with your doctor or pharmacist about potential interactions.
Other Precautions
Avoid grapefruit juice while taking Sildenafil. It can increase the drug’s concentration in your blood, potentially causing side effects. Also, Sildenafil isn’t recommended for people with severe liver or kidney disease.
Contraindications Summary
| Nitrates | Nitroglycerin, Isosorbide | Severe hypotension |
| Alpha-blockers | Terazosin, Doxazosin | Hypotension |
| CYP3A4 Inhibitors | Ketoconazole, Erythromycin | Increased Sildenafil levels |
Remember: This information is not a substitute for professional medical advice. Always consult your doctor before starting or stopping any medication.
