Prednisone, while effective, carries potential side effects. Common ones include increased appetite and weight gain, fluid retention (causing swelling), mood changes (irritability, anxiety, or depression), insomnia, and increased blood sugar. These usually lessen as your dose decreases.
More Serious Side Effects
Less common but more serious side effects require immediate medical attention. These include increased risk of infections due to suppressed immunity, thinning of bones (osteoporosis), high blood pressure, stomach ulcers, and cataracts or glaucoma. Long-term use significantly increases the risk of these problems. Always inform your doctor about any existing health conditions before starting Prednisone.
Your doctor will carefully monitor your progress and adjust your dosage as needed to minimize side effects. Open communication with your physician is critical for safe and effective Prednisone use. Report any unusual symptoms promptly.
Medication Interactions
Prednisone can interact with other medications. Always provide your doctor with a complete list of all medications, supplements, and herbal remedies you are taking. This includes over-the-counter drugs. This prevents dangerous interactions and ensures your safety.


