Sildenafil, while generally well-tolerated, can cause side effects. Common ones include headache, facial flushing, and nasal congestion. Less frequent but more serious effects may include vision changes (blurred vision, blue tinge to vision), hearing loss, and prolonged erection (priapism). Seek immediate medical attention if you experience a prolonged erection lasting more than four hours.
Sildenafil interacts with several medications. It should not be taken with nitrates (used to treat angina) as this combination can cause a dangerous drop in blood pressure. It can also interact with alpha-blockers (used to treat high blood pressure and enlarged prostate), potentially leading to dizziness or fainting. Consult your doctor about potential interactions if you are taking other medications, including those for heart conditions, liver disease, or kidney disease.
| Nitrates | Dangerous drop in blood pressure | Do not take sildenafil with nitrates. |
| Alpha-blockers | Dizziness, fainting | Your doctor may adjust dosages or suggest alternatives. |
| CYP3A4 inhibitors (e. g., ketoconazole, erythromycin) | Increased sildenafil levels | Your doctor may adjust the sildenafil dose. |
| CYP3A4 inducers (e. g., rifampin) | Decreased sildenafil levels | Your doctor may need to adjust the sildenafil dose. |
Always inform your doctor about all medications and supplements you are taking before starting sildenafil. This information helps ensure safe and effective use. Remember to follow your doctor’s instructions carefully and report any concerning side effects immediately.
