Always inform your doctor about all medications you take, including over-the-counter drugs and supplements, before starting Cialis. This helps prevent dangerous interactions.
Common side effects include headache, flushing, nasal congestion, and indigestion. These are usually mild and temporary. However, seek immediate medical attention if you experience more serious side effects such as prolonged erection (priapism), sudden vision loss, or hearing loss.
| Nitrates | Can cause a dangerous drop in blood pressure. Do not take Cialis if you use nitrates. |
| Alpha-blockers | May increase the risk of low blood pressure. Your doctor may adjust your dosage. |
| CYP3A4 inhibitors (e. g., ketoconazole, ritonavir) | Can increase Cialis levels in your blood, potentially increasing side effects. Your doctor may adjust your dosage. |
| CYP3A4 inducers (e. g., rifampin, St. John’s Wort) | Can decrease Cialis levels in your blood, reducing its effectiveness. |
Grapefruit juice can also interact with Cialis, potentially raising blood levels. Avoid grapefruit juice while taking Cialis.
This information is not exhaustive. Consult your physician or pharmacist for a complete list of potential drug interactions and side effects specific to your health condition and other medications you are taking.


