Interactions with Other Medications and Substances

Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs, before starting Sildenafil citrate. This includes nitrates (found in some heart medications), as combining them with Sildenafil can cause a dangerous drop in blood pressure. Alpha-blockers, often prescribed for high blood pressure or enlarged prostate, can also interact, potentially leading to dizziness or fainting.

Specific Interactions to Note

Sildenafil’s metabolism can be affected by medications like ketoconazole (antifungal) and erythromycin (antibiotic), potentially increasing Sildenafil’s effects and side effects. Conversely, rifampin (antibiotic) can decrease Sildenafil’s effectiveness. Grapefruit juice inhibits the enzymes that break down Sildenafil, increasing its concentration in the blood. Avoid grapefruit juice while taking Sildenafil. Alcohol consumption can exacerbate Sildenafil’s side effects, such as headaches and dizziness. Consult your doctor about safe alcohol consumption limits while using Sildenafil.

This information is not exhaustive. Always consult your physician or pharmacist for personalized advice on potential drug interactions. They can assess your individual health status and medication profile to provide tailored recommendations and ensure your safety.