Interactions with Other Medications and Substances

Always inform your doctor about all medications you are taking, including over-the-counter drugs, herbal supplements, and recreational drugs. This is crucial for your safety.

Nitrates: A Dangerous Combination

Never combine Viagra generic (sildenafil) with nitrates, found in medications for chest pain (angina). This combination can cause a dangerous drop in blood pressure, leading to serious health problems, including heart attack or stroke.

Other Medications to Discuss

Certain medications can affect how sildenafil works or increase the risk of side effects. These include alpha-blockers (used for high blood pressure and enlarged prostate), certain antibiotics, antifungals, and HIV medications. Your doctor can help assess potential interactions.

Alcohol and Grapefruit Juice: Moderation is Key

Excessive alcohol consumption can worsen sildenafil’s side effects. Similarly, grapefruit juice can interfere with sildenafil’s metabolism, potentially leading to higher blood levels of the drug. Moderate your intake of both.

Summary of Potential Interactions

Medication Class Potential Interaction Recommendation
Nitrates Severe drop in blood pressure Avoid combining
Alpha-blockers Increased risk of low blood pressure Discuss with doctor before use
Certain Antibiotics & Antifungals Altered sildenafil metabolism Doctor monitoring may be required
HIV Medications (Protease Inhibitors) Increased sildenafil levels Dosage adjustment might be needed
Alcohol & Grapefruit Juice Increased side effects, altered metabolism Moderate consumption

Consult Your Doctor

This information is not exhaustive. Always consult your doctor or pharmacist before starting sildenafil, especially if you have pre-existing health conditions or are taking other medications. They can help determine the safest and most effective approach for you.