Always inform your doctor about all medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. This is crucial for safe Tadalafil use.
Nitrates and Tadalafil
Combining Tadalafil with nitrates (found in some heart medications) can cause a dangerous drop in blood pressure. This interaction can lead to dizziness, fainting, or even heart attack. Avoid using Tadalafil if you are taking nitrates.
Alpha-Blockers and Tadalafil
Concurrent use of Tadalafil and alpha-blockers (used to treat high blood pressure or enlarged prostate) may significantly lower blood pressure. Your doctor might adjust your dosage or recommend alternative treatments.
CYP3A4 Inhibitors and Tadalafil
Medications that inhibit the CYP3A4 enzyme (like ketoconazole, itraconazole, ritonavir) can increase Tadalafil levels in your blood, potentially leading to side effects. Your doctor may suggest a lower Tadalafil dose.
Other Potential Interactions
Tadalafil may also interact with other medications, such as:
| Antihypertensives (other than alpha-blockers) | Increased blood pressure lowering effect |
| Antifungal medications (other than azoles) | Potentially altered Tadalafil metabolism |
| Antibiotics (macrolides) | Potentially increased Tadalafil levels |
This list isn’t exhaustive, and individual responses to drug interactions vary. Consult your doctor or pharmacist for a complete assessment of potential interactions before starting Tadalafil.
Alcohol and Tadalafil
Excessive alcohol consumption can increase the risk of Tadalafil side effects, particularly low blood pressure. Moderate alcohol intake is generally advised.
