Drug Interactions with Doxycycline in Canines

Always inform your veterinarian about all medications your dog is taking, including supplements and over-the-counter drugs, before starting doxycycline. This helps prevent harmful interactions.

Dairy Products and Antacids

Doxycycline’s absorption decreases significantly when administered with dairy products or antacids containing calcium, magnesium, aluminum, or iron. Administer doxycycline at least two hours before or four hours after these substances.

Warfarin

Concurrent use of doxycycline and warfarin (a blood thinner) can increase the risk of bleeding. Close monitoring of your dog’s blood clotting time is crucial during combined therapy. Your vet will likely perform regular blood tests.

Other Antibiotics

Doxycycline may interact negatively with other antibiotics, potentially reducing their effectiveness. Discuss any other antibiotics your dog is currently receiving with your veterinarian to assess potential conflicts.

Seizure Medications

Certain seizure medications can interact with doxycycline, potentially altering drug levels. This requires careful monitoring by your veterinarian, possibly including adjustments to medication dosages. Always consult your veterinarian before making any changes to your dog’s medication regimen.

Sunscreens

Doxycycline can increase photosensitivity, making your dog more susceptible to sunburn. Limit sun exposure during treatment or use pet-safe sunscreen on exposed areas. This is particularly important during peak sun hours.