Drug Interactions with Cialis

Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies, before starting Cialis. This includes nitrates, often used for chest pain. Combining these can cause a dangerous drop in blood pressure.

Nitrates and Similar Medications

Nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate are examples of medications that interact dangerously with Cialis. This interaction can lead to severe hypotension (low blood pressure), potentially causing dizziness, fainting, or even heart attack. Avoid concurrent use.

Alpha-Blockers

Alpha-blockers, frequently prescribed for high blood pressure or enlarged prostate, can also interact with Cialis. This combination might significantly lower blood pressure, leading to similar risks as with nitrates. Your doctor should carefully monitor you if both medications are necessary.

CYP3A4 Inhibitors

Some medications inhibit the CYP3A4 enzyme, which metabolizes Cialis. This can increase Cialis levels in your blood, potentially intensifying side effects. Examples include ketoconazole, itraconazole, erythromycin, and clarithromycin. Your doctor may adjust your Cialis dosage if you’re taking one of these.

Other Interactions

Cialis can interact with other medications, including some antifungals, HIV protease inhibitors, and certain antibiotics. A complete list of potential interactions is available in the Cialis medication guide. Always consult your physician or pharmacist for personalized advice.