Cialis works by inhibiting the enzyme phosphodiesterase-5 (PDE5). This enzyme breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection.
By blocking PDE5, Cialis allows cGMP levels to rise. Increased cGMP relaxes the smooth muscles in the blood vessels of the penis, leading to increased blood flow. This increased blood flow is what causes an erection.
Understanding cGMP’s Role
CGMP acts as a messenger within the body. When sexually stimulated, nitric oxide is released, triggering a cascade of events that lead to increased cGMP production. This increase then allows for the relaxation of penile muscles, facilitating blood flow and an erection.
Cialis’s Specific Action and Duration
Cialis’s unique formulation allows it to remain effective for a longer duration than some other medications in its class. This extended half-life means the effects can last up to 36 hours. This contrasts with shorter-acting medications.
| Cialis | Up to 36 hours |
| (Other medications would go here for comparison) | (Their durations) |
Factors Affecting Cialis’s Effectiveness
Several factors influence Cialis’s effectiveness, including pre-existing health conditions, other medications, and individual responses. Always consult a doctor before using Cialis or any medication for erectile dysfunction.
