Viagra, or sildenafil, primarily works by inhibiting phosphodiesterase-5 (PDE5). This enzyme normally breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for penile erection.
By blocking PDE5, Viagra allows cGMP to persist. Higher cGMP levels relax the smooth muscles in the blood vessels of the penis, increasing blood flow.
This increased blood flow leads to penile engorgement and facilitates the achievement and maintenance of an erection in response to sexual stimulation. It’s important to remember that Viagra does not cause erections spontaneously; sexual stimulation is still necessary.
The effect of Viagra typically lasts for four to five hours. Individual responses vary, and factors such as age, overall health, and medication interactions can influence its duration and effectiveness.
Consult your doctor before using Viagra, especially if you have pre-existing health conditions or are taking other medications. They can assess your suitability and provide personalized advice.
