Clomiphene citrate works by blocking estrogen receptors in the hypothalamus and pituitary gland. This blockage tricks your body into thinking estrogen levels are low. Consequently, the pituitary gland releases more follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Increased FSH and LH Production
The increased FSH stimulates follicle growth in the ovaries, leading to the development of mature eggs. The elevated LH triggers ovulation, the release of a mature egg from the ovary. This process is crucial for conception.
Selective Estrogen Receptor Modulation
It’s important to note that clomiphene citrate doesn’t completely block estrogen receptors; it selectively modulates their activity. This selective action is why it can stimulate ovulation without causing widespread estrogen deficiency.
Individual Responses Vary
The exact response to clomiphene citrate varies greatly depending on individual factors, including age, ovarian reserve, and overall health. Some women respond well with a single cycle, while others might require multiple cycles to achieve ovulation.
Potential Side Effects
Remember that while clomiphene citrate is generally safe, it can cause side effects such as hot flashes, mood swings, and visual disturbances. Discuss these potential effects with your doctor before starting treatment.
Monitoring and Dosage Adjustments
Your doctor will monitor your response to clomiphene citrate through blood tests and ultrasounds. This monitoring allows for appropriate dosage adjustments to maximize effectiveness and minimize risks. Regular check-ups are necessary to guide treatment.
