Vardenafil, like other phosphodiesterase-5 (PDE5) inhibitors, can cause side effects. Common ones include headache, flushing, nasal congestion, and indigestion. These typically are mild and transient. Less frequent side effects include back pain, muscle aches, and visual disturbances such as changes in color vision or blurred vision. Rarely, more serious side effects such as hearing loss or a prolonged erection (priapism) may occur. Seek immediate medical attention if you experience a prolonged erection lasting more than four hours.
Interactions with Other Medications
Vardenafil interacts with nitrates, often found in medications for chest pain (angina). Combining them can cause a dangerous drop in blood pressure. You should also inform your doctor about any other medications you’re taking, including alpha-blockers (used for high blood pressure or enlarged prostate), antifungals, antibiotics, or HIV protease inhibitors, as these can affect vardenafil’s effectiveness or increase the risk of side effects. Grapefruit juice can also interact negatively; avoid it while using vardenafil.
Specific Considerations
Men with heart conditions, low blood pressure, or severe liver or kidney problems should discuss vardenafil use with their doctor before starting treatment. Similarly, individuals with a history of stroke or eye problems should have a thorough consultation. Always follow your doctor’s instructions precisely regarding dosage and frequency of use.