Triamterene/HCTZ can cause various side effects, some common, others less so. Always consult your doctor if you experience anything concerning.
- Common side effects: Dizziness, headache, nausea, diarrhea, and dry mouth are frequently reported. These typically lessen as your body adjusts. Less common but important side effects: Muscle cramps, weakness, and increased thirst can occur. Changes in potassium levels are possible, so regular blood tests are often recommended. Rare but serious side effects: Allergic reactions (rash, swelling, difficulty breathing), jaundice, and kidney problems warrant immediate medical attention.
Drug interactions are a significant consideration. This combination interacts with several medications, affecting their absorption and efficacy. Here are some key interactions to watch out for:
ACE inhibitors and ARBs: Combining Triamterene/HCTZ with these medications can lead to dangerously high potassium levels (hyperkalemia). Lithium: Triamterene/HCTZ can increase lithium levels, potentially causing toxicity. Close monitoring is necessary. Digoxin: This medication’s effectiveness can be altered by Triamterene/HCTZ, requiring careful dose adjustments. Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs can reduce the effectiveness of Triamterene/HCTZ and increase the risk of kidney problems.
This list is not exhaustive. Inform your doctor about all medications, supplements, and herbal remedies you’re taking, to avoid potential complications. Regular monitoring of your blood pressure, potassium levels, and kidney function is crucial while on this medication.
