Always inform your doctor about all medications you’re taking, including over-the-counter drugs, herbal remedies, and supplements. This includes nitrates, which can cause a dangerous drop in blood pressure when combined with Cialis. Avoid combining them.
Nitrates and Similar Medications
- Nitroglycerin (for chest pain) Isosorbide dinitrate and isosorbide mononitrate (for angina) Amyl nitrite (for angina)
Using Cialis with these medications can lead to severe hypotension (low blood pressure).
Other Potential Interactions
Alpha-blockers: These medications, often used for high blood pressure or prostate problems, can increase the risk of low blood pressure when combined with Cialis. Your doctor might adjust your dosage. CYP3A4 inhibitors: Certain medications, like ketoconazole and ritonavir, can increase Cialis levels in your blood, potentially leading to side effects. Your doctor will assess if dosage adjustments are necessary. CYP3A4 inducers: Conversely, some medications like rifampin can decrease Cialis levels. Discuss dosage with your doctor. Blood thinners: While not a direct interaction, the combined effect on bleeding risk needs careful monitoring.
Grapefruit Juice
Grapefruit juice inhibits the enzymes that metabolize Cialis, leading to increased blood levels. Avoid grapefruit juice while taking Cialis.
Always Consult Your Doctor
This information isn’t exhaustive. Discuss all your medications with your doctor or pharmacist before starting Cialis to ensure safety and effectiveness.