Phosphodiesterase-5 (PDE5) inhibitors, the primary active ingredient in most Ed pills, increase blood flow to the penis. They achieve this by blocking PDE5, an enzyme that breaks down cyclic GMP (cGMP), a crucial molecule for penile erection. Higher cGMP levels relax the muscles in the blood vessels of the penis, allowing more blood to flow in.
This increased blood flow leads to engorgement of the erectile tissue, resulting in a firmer and longer-lasting erection. Different PDE5 inhibitors may vary slightly in their absorption and duration of action.
Proper sexual stimulation remains necessary; the pills don’t spontaneously cause erections. They simply enhance the body’s natural response to sexual stimulation.
Always consult a doctor before taking any Ed medication. Your doctor can assess your overall health, identify potential drug interactions, and determine the appropriate dosage and type of medication for your specific needs. They can also discuss potential side effects and address any concerns you may have.